Pharmacokinetic visualization explorer
Deterministic model predictions for education. These views do not identify safe doses or establish clinical validation.
Scenario
Open this page from Research tools to copy your current settings. Sweeps use nominal parameters, without uncertainty sampling or fitting to observations. The full selected simulation duration is retained.
Two-input explorer
Generate a grid, then select a heatmap cell to inspect its curves and drug accounting.
Compare grid scenarios
3D is optional. Rotate to explore; use the heatmap buttons for exact values and keyboard selection. The surface connects sampled predictions and does not add simulated data between grid points.
Selected scenario
Plasma acyclovir (blue) · CSF acyclovir (orange, dashed) · plasma CMMG (purple, dotted). All concentrations in mg/L.
Plasma–CSF trajectory
Each point pairs simultaneous plasma and cerebrospinal fluid concentrations. Arrows follow increasing time. The time slider selects a sample on the path.
Compartment animation
Per-exchange PD removal
Where did the input go?
Widths show mg of acyclovir-equivalent input accounted for by the selected time. Oral input includes only the model-bioavailable acyclovir equivalent; unabsorbed tablet mass is outside this balance. CMMG formation is cumulative acyclovir converted, not current CMMG mass. PD fluid is counted separately from drug discarded at modeled exchange/session boundaries. CSF is excluded because it is not an integrated mass compartment. Intercompartmental recirculation is represented by amounts remaining, avoiding double counting.